Background:PROM1, also named as PROML1, CD133 and AC133, belongs to the prominin family. PROM1 interacts with PCDH21 and with actin filaments. CD133 is a cance stem cell marker. Defects in PROM1 are the cause of retinitis pigmentosa type 41 (RP41)which also known as retinal degeneration autosomal recessive prominin-related. Defects in PROM1 are the cause of cone-rod dystrophy type 12 (CORD12). Defects in PROM1 are the cause of Stargardt disease type 4 (STGD4). Defects in PROM1 are the cause of retinal macular dys trophy type 2 (MCDR2). The antibody recognizes transcript variant 1,6,7 of PROM1.
Storage/Stability:Store at 4°C or -20°C (with 50% glycerol); Minimize freeze-thaw cycles; Non-hazardous.
Limitation:For research use only and are not intended for diagnostic or therapeutic use.
Recommended Dilutions:WB: 1:500-1000。
Applications:WB, ELISA。 Other applications have not been tested。
Formulation:Each vial at least contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.1% sodium azide.