Background:This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Altername:RP41; AC133; CD133; MCDR2; STGD4; CORD12
Immunogen:Synthesized peptide of human CD133 (AA: 20-36, GGQPSSTDAPK AWNYELc)
Storage/Stability:Store at 4℃, for long term storage, store at -20℃。
Form of Antibody:Ascitic fluid containing 0.03% sodium azide.
Recommended Dilutions:IHC:1/200 - 1/1000, FC:1/200 - 1/400, ELISA: Propose dilution 1/10000。
Applications:IHC, FC, ELISA。 Not yet tested in other applications。
Research Area:Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells